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Cleo Mottley is the daughter of Jim T. Mottley and Emma Mae Kneeland. Her siblings were Dorothy Mottley, Earnest Mottley, Regina Mottley, Viola Mottley, Jerry Mottley, Morris Mottley, Leshell Mottley, Alfred Mottley, Karen Mottley, Angela Mottley, Mary Mottley, Agnettia Mottley, Jim Mottley, Charlie Mottley.
Cleo Mottley's husband is Baymon Barry. They had three known children named Baymon Barry, Comeshia Barry, and Comelia Barry.