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Mattie Bell Caldwell is the daughter of Samuel Caldwell (?-1986) and Albertine Williams (1889-1971). Her siblings were Elvis Caldwell (1912-2001), Samella Caldwell, Minnie Lue Caldwell, Cullen Caldwell (1917-1998), Alfredia Caldwell, Joe Dennis Caldwell, Richard Caldwell.
Mattie Bell Caldwell's husband is not known. They had four known children named Eric Caldwell, Sandra Denise Caldwell, Monica Caldwell, and Kevin Caldwell.